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PRALUENT® reduces the relative risk of MACE* by 15%1

In ODYSSEY OUTCOMES, on top of high-intensity/maximally tolerated statins, PRALUENT significantly reduced the risk of MACE vs placebo (HR 0.85, 95% CI 0.78, 0.93; p<0.001)1

 

CV INDICATION

PRALUENT® (alirocumab) is indicated in adults with established atherosclerotic cardiovascular disease to reduce cardiovascular risk by lowering LDL-C levels as an adjunct to correction of other risk factors:
-in combination with the maximum tolerated dose of a statin with or without other lipid-lowering therapies, or
- alone or in combination with other lipid-lowering therapies in patients who are statin-intolerant or for whom a statin is contraindicated2
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Praluent SMC
 

RESOURCES FOR YOUR PATIENTS

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*MACE defined in ODYSSEY OUTCOMES clinical trial as composite of coronary heart disease death, non-fatal myocardial infarction, fatal and non-fatal ischaemic stroke, or unstable angina requiring hospitalisation1
CI, confidence interval; CV, cardiovascular; HR, hazard ratio; LDL-C, low-density lipoprotein cholesterol; MACE, Major adverse cardiovascular event; MI, myocardial infarction

References

  1. Schwartz GG et al. Alirocumab and cardiovascular outcomes after acute coronary syndrome. N Engl J Med. 2018; 379:2097-2107.
  2. Praluent Summary of Product Characteristics. Available at https://www.medicines.org.uk/emc/medicine/30956. Accessed March 2019.
   
Sanofi UK

Adverse events should be reported.

Reporting forms and information can be found at yellowcard.mhra.gov.uk.

Adverse events should also be reported to Sanofi on 0800 090 2314 or uk-drugsafety@sanofi.com.

SAGB.ALI.19.02.0295(1) | July 2019