• KEY LEARNINGS IN DYSLIPIDAEMIA - Professor Kausik Ray


    Watch this short video to hear Professor Kausik Ray from University College London share a summary of key learnings in dyslipidaemia from the European Atherosclerosis Society (EAS) congress 2021

    Cardiovascular disease is a major financial burden to the NHS and a leading cause of disability and death in the UK1

    The NHS Long Term Plan aims to prevent up to 150,000 cases of heart attack, stroke and dementia over the next 10 years.2,3

    The plan of action to tackle CVD includes3

    There are clear recommendations in the UK regarding optimal cholesterol levels4, 5

    People with high levels of LDL-C should pay particular attention to keeping their cholesterol levels within a recommended range4, 5

    For people with existing CVD and uncontrolled LDL-C

    View detailed recommendations

    In an observational study, only 2 in 5 UK patients at very high cardiovascular risk achieved the ESC/EAS recommended goal of <1.8 mmol/L despite treatment with statins6

    Despite recommendations regarding optimal cholesterol levels, an observational study found that half of all high-risk cardiovascular disease patients still have LDL-C levels that are too high6

    In an observational study, when hospitalized for ACS, only 1 in 4 people with high CV risk and treated with lipid-lowering therapy were at the ESC/EAS recommended goal of <1.8mmol/L7

    An audit (MINAP)* in 2016, identified that diagnosed hyperlipidaemia (elevation of LDL-C levels requiring treatment) was more prevalent in people experiencing a second heart attack than in those experiencing their first8

    ACCELERATED ACCESS COLLABORATIVE

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    *MINAP: Myocardial Ischaemia National Audit Project
    †The term ‘baseline’ referes to the LDL-C level in a person not taking any LDL-C lowering medication. In people who are taking LDL-C-lowering medication(s), the projected baseline (untreated) LDL-C levels should be estimated, based on the average LDL-C-lowering efficacy of the given medication or combination of medications.14

    1. Public Health England Press Release, September 2018. ‘Prevention must be at the heart of the NHS long-term plan’. Available at: https://www.gov.uk/government/news/prevention-must-be-the-heart-of-the-nhs-long-term-plan/ Last accessed: August 2021
    2. The NHS Long Term Plan, January 2019. Available at: https://www.longtermplan.nhs.uk/wp-content/uploads/2019/08/nhs-long-term-plan-version-1.2.pdf Last accessed: August 2021
    3. Public Health England. Health matters: preventing cardiovascular disease, February 2019. Available at: https://www.gov.uk/government/publications/health-matters-preventing-cardiovascular-disease/health-matters-preventing-cardiovascular-disease Last accessed: August 2021
    4. National Institute for Health and Care Excellence. CG71. Published 2008, last updated November 2017. Available at: https://www.nice.org.uk/guidance/cg71 Last accessed: August 2021
    5. Piepoli MF et al. Eur Heart J. 2016; 37:2315-81
    6. Gitt AK et al. Data in brief. 2016; 9:616-20
    7. Gitt AK et al. Atherosclerosis. 2017; 266:158-22
    8. Myocardial Ischaemia National Audit Project (MINAP) Annual Public Report April 2015 – March 2016
    9. Mach F et al. Eur Heart J. 2019; doi:10.1093/eurheartj/ehz455. [Epub ahead of print]